Child-Resistant Packaging for Pharmaceutical Dosage Forms

The major oral solid medicines are sold in blister and strips packaging, which are packaged in a carton box. Children, who managed to open a box like that, while unsupervised, are in great danger of being poisoned by swallowing the contents. High barrier child resistant packaging usually requires a special trick to open it. 

The aim is to design and validate the performance of an innovative child-resistant packaging system with unique features. The materials used are plastic grade, click-lock system, and blister packs. A test was conducted on test panels of 100 healthy children between 42 and 51 months where they were asked to open a pack. 

Every panel was divided into 3 groups, namely. 30 children from 42-44 months, 40 children 45-48 months, and 30 children 49-51 months. 100 healthy adult panels were divided into 3 groups, namely. 25 adults 18-40 years, 25 adults 40-59 years, and 50 adults 60-70 years. The results showed only 6% of children managed to open child-resistant packaging, while 94% failed to open CRP in 5 minutes.

In the case of adults, 96% managed to open CRP without imposing difficulties. There is a development of CRP prototypes, which can be used for packaging pharmaceutical products. CRP deprived children to have access to medicated packaging system, which resulted in devoid of any poisonous effect to the children.